| 产品概述: |
Alpha2-macroglobulin is a major serum protein with diverse functions, including inhibition of protease activity and binding of growth factors, cytokines, and disease factors. It is also a panproteinase inhibitor that is found immunohistochemically in neuritic plaques.
Alpha-2-macroglobulin is able to inactivate an enormous variety of proteinases (including serine-, cysteine-, aspartic- and metalloproteinases). Alpha-2-macroglobulin has in its structure a 35 aminoacid "bait" region. Proteinases binding and cleaving the bait region become bound to alpha2M. The proteinase-α2M complex is recognised by macrophage receptors and cleared from the system.
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| 特异性: |
The antibody is a Goat polyclonal antibody raised against A2M. It has been selected for its ability to recognize A2M in ELISA Kit and western blotting.
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| 使用方法: |
WB=1:100-500 ELISA=1:500-1000
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
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| 稳定性: |
Store at -20°C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-8°C.
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| 存储: |
Shipped at 2-8°C. Upon delivery aliquot and store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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| 存储缓冲液: |
0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
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| 注意事项: |
This product is for research use only, not for diagnostic or therapeutic use.
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