| 产品概述: |
Apolipoprotein C-III is a very low density lipoprotein (VLDL) protein. APOC3 inhibits lipoprotein lipase and hepatic lipase; it is thought to delay catabolism of triglyceride-rich particles. The APOA1, APOC3 and APOA4 genes are closely linked in both rat and human genomes. The A-I and A-IV genes are transcribed from the same strand, while the A-1 and C-III genes are convergently transcribed.
An increase in apoC-III levels induces the development of hypertriglyceridemia.Lately, two novel susceptibility haplotypes i.e. P2-S2-X1 and P1-S2-X1 have been discovered in ApoAI-CIII-AIV gene cluster on chromosme 11q23, who confer approximately threefold higher risk of coronary heart disease in normal as well as non-insulin diabetes mellitus.
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| 特异性: |
The antibody is a Goat polyclonal antibody raised against APOC-III. It has been selected for its ability to recognize APOC-III in ELISA Kit and western blotting.
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| 使用方法: |
WB=1:100-500 ELISA=1:500-1000
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
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| 稳定性: |
Store at -20°C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-8°C.
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| 存储: |
Shipped at 2-8°C. Upon delivery aliquot and store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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| 存储缓冲液: |
0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
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| 注意事项: |
This product is for research use only, not for diagnostic or therapeutic use.
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