首页 // 产品中心 // 蛋白

Recombinant Human Geminin (GMNN) Protein


生产种属

Human

来源

Prokaryotic expression

宿主

E. coli

同义词

GMNN; Gem

浓度

1 mg/mL

形态

Lyophilized or Liquid

纯度

> 95% as determined by SDS-PAGE

序列

O75496

标签

N-terminal His-tag

纯化方式

Affinity purification

分子量

12 kDa

应用

Western blotting,ELISA;SDS-PAGE;Antigen;

货号

AP50145HU

规格

100μg 500μg 1mg

价格

查询

货期

3-5 working days

说明书

登陆
产品概述:
Geminin was originally identified as an inhibitor of DNA replication and substrate of the anaphase promoting complex (APC). Coincidentally, geminin was also shown to expand the neural plate in the developing Xenopus embryo. Inhibits DNA replication by preventing the incorporation of MCM complex into pre-replication complex (pre-RC). It is degraded during the mitotic phase of the cell cycle. Its destruction at the metaphase-anaphase transition permits replication in the succeeding cell cycle. Inhibits the transcriptional activity of a subset of Hox proteins, enrolling them in cell proliferative control.
使用方法:
Reconstitute in PBS or others.
稳定性:
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
存储:
Store it under sterile conditions at -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. Samples are stable for up to twelve months from date of receipt at -80℃.
存储缓冲液:
Lyophilized from 20 mM PB, 300 mM NaCl,pH 7.4
注意事项:
This product is for research use only, not for diagnostic or therapeutic use.