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Recombinant Human Prostacyclin (PGI) Protein


生产种属

Human

来源

Prokaryotic expression

宿主

E. coli

同义词

Prostaglandin I2; PGI2

浓度

1 mg/mL

形态

Lyophilized or Liquid

纯度

> 95% as determined by SDS-PAGE

序列

N/A

标签

N/A

纯化方式

Affinity purification

分子量

N/A

应用

Western blotting,ELISA;SDS-PAGE;Antigen;

货号

AP50025HU

规格

100μg 500μg 1mg

价格

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货期

3-5 working days

说明书

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产品概述:
Prostacyclin is produced in endothelial cells from prostaglandin H2 (PGH2) by the action of the enzyme prostacyclin synthase. Although prostacyclin is considered an independent mediator, it is called PGI2 in eicosanoid nomenclature, and is a member of the prostanoids.The series-3 prostaglandin PGH3 also follows the prostacyclin synthase pathway, yielding another prostacyclin, PGI3. The unqualified term 'prostacyclin' usually refers to PGI2. PGI2 is derived from the ω-6 arachidonic acid. PGI3 is derived from the ω-3 EPA. Prostacyclin (PGI2) chiefly prevents formation of the platelet plug involved in primary hemostasis (a part of blood clot formation). It does this by inhibiting platelet activation. It is also an effective vasodilator. Prostacyclin's interactions in contrast to thromboxane (TXA2), another eicosanoid, strongly suggest a mechanism of cardiovascular homeostasis between the two hormones in relation to vascular damage.
使用方法:
Reconstitute in PBS or others.
稳定性:
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
存储:
Store it under sterile conditions at -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. Samples are stable for up to twelve months from date of receipt at -80℃.
存储缓冲液:
Lyophilized from sterile 20mM PB,240mM NaCl,PH6.21.
注意事项:
This product is for research use only, not for diagnostic or therapeutic use.