Glucocorticoids (GCs) are synthesised de novo by peripheral tissues and the adrenal cortex of the hypothalamic–pituitary–adrenal axis. Skin expresses an enzyme called 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1), which reduces cortisone to the active hormone cortisol which activates GC receptors.
Product: Mouse Corticosteroid 11-beta-dehydrogenase isozyme 1 (HSD11B1) ELISA Kit
Pub Date:2025-01-30 IF: 3.500
Ureaplasma species can cause systemic infections in immunocompromised hosts, including lung transplant recipients. Here, we investigated the impact of prior exposure to Ureaplasma urealyticum on the risk of U. urealyticum and Ureaplasma parvum infection in mice subjected to an immunosuppression regimen similar to that administered to solid organ transplant recipients.
Product: Mouse Ureaplasma urealyticum antibody (UU-Ab) ELISA Kit
Pub Date:2024-11-19 IF: 3.700
Obesity is a deleterious medical condition that can lead to lipid metabolism dysregulation and various metabolic disorders. The lipid-reducing and hypoglycemic effects of Rosa rugosa have been demonstrated both in vitro and in vivo. However, the mechanisms of the anti-obesity components and gut microbiota regulating potential of R.
Product: Mouse Leptin (LEP) ELISA Kit Mouse Insulin (INS) ELISA Kit
Pub Date:2024-11-04 IF: 3.800
Adrenocortical carcinoma (ACC) is a rare and aggressive malignancy characterised by diagnostic challenges, high recurrence rates, and poor prognosis. This study explored the role microRNA (miRNA) processing genes in ACC, and their potential role as diagnostic and prognostic biomarkers.
Product: Human Protein argonaute-2 (EIF2C2) ELISA Kit Human Microprocessor complex subunit DGCR8 (DGCR8) ELISA Kit Human Ribonuclease 3 (RNASEN) ELISA Kit Human GTP-binding nuclear protein Ran (RAN) ELISA Kit Human Exportin-5 (XPO5) ELISA Kit
Pub Date:2024-10-01 IF: 4.100
Traumatic brain injury (TBI) is an acquired insult to the brain caused by an external mechanical force, potentially resulting in temporary or permanent impairment. Microglia, the resident immune cells of the central nervous system, are activated in response to TBI, participating in tissue repair process.
Product: Mouse C-C motif chemokine 5 (CCL5) ELISA Kit
Pub Date:2024-09-30 IF: 8.200
Objective. To explore and validate the value of clinical parameters combined with plasma biomarkers for predicting acute respiratory distress syndrome (ARDS) in patients of high risks in the surgical intensive care unit (SICU).
Product: Human Angiotensin 2 (ANG-2) ELISA Kit Human Krebs yon den Lundgen-6 (KL-6) ELISA Kit Human Receptor for advanced glycation end products (RAGE/AGER) ELISA Kit
Pub Date:2024-08-29 IF: 4.664