Adrenocortical carcinoma (ACC) is a rare and aggressive malignancy. Current treatment algorithms are associated with diagnostic limitations, high recurrence rates and poor prognosis. Identifying specific biomarkers that facilitate accurate diagnosis and provide prognostic insights could significantly enhance the patient outcomes in ACC.
Product: Human Protein argonaute-2 (EIF2C2) ELISA Kit Human Microprocessor complex subunit DGCR8 (DGCR8) ELISA Kit Human Ribonuclease 3 (RNASEN) ELISA Kit Human GTP-binding nuclear protein Ran (RAN) ELISA Kit Human Exportin-5 (XPO5) ELISA Kit
Pub Date:2024-03-27
As a famous prescription in China, AnGong NiuHuang (AGNH) pill exerts good neuroprotection for ischaemic stroke (IS), but its mechanism is still unclear. In this study, the neuroprotection of AGNH was evaluated in the rat IS model which were established with the surgery of middle cerebral artery occlusion (MCAO), and the potential mechanism was elucidated by transcriptomic analysis and metabolomic analysis.
Product: Mouse TYRO protein tyrosine kinase-binding protein (TYROBP) ELISA Kit
Pub Date:2024-02-24 IF: 5.100
Elevated level of active glucocorticoid (GC) deteriorates skin barrier function. 11β-Hydroxysteroid dehydrogenase type 1 (11β-HSD1) is an NADPH-dependent enzyme converting inactive GC to active GC. Elevated active GC due to increased 11β-HSD1 expression might contribute to barrier impairment in aged skin and diabetic skin.
Product: Mouse Corticosteroid 11-beta-dehydrogenase isozyme 1 (HSD11B1) ELISA Kit
Pub Date:2024-01-12
Microglia are highly heterogeneous as resident immune cells in the central nervous system. Although the proinflammatory phenotype of microglia is driven by the metabolic transformation in the disease state, the mechanism of metabolic reprogramming in microglia and whether it affects surrounding astrocyte progenitors have not been well elucidated.
Product: Mouse Leucine-rich repeat-containing protein 15 (LRRC15) ELISA Kit
Pub Date:2023-12-14 IF: 11.800
Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease characterized by rapid progression and high mortality.
Product: Monkey Superoxide dismutase 1, soluble (SOD1) ELISA Kit
Pub Date:2023-11-23
Heart failure is a serious condition that results from the extensive loss of specialized cardiac muscle cells called cardiomyocytes (CMs), typically caused by myocardial infarction (MI).
Product: Mouse Alanine Aminotransferase (ALT) ELISA Kit Mouse Aspartate Aminotransferase (AST) ELISA Kit
Pub Date:2023-11-20 IF: 17.100