Triple-negative breast cancer (TNBC) urgently requires new therapeutic strategies due to the limited efficacy of conventional treatments. Recently, PANoptosis, an integrated form of apoptosis, necroptosis, and pyroptosis, has emerged as a promising target in cancer therapy, though effective agents remain scarce.
Product: Human High mobility group protein B1 (HMGB1) ELISA Kit
Pub Date:2025-08-22 IF: 6.600
Hepatocellular carcinoma (HCC) is frequently associated with Yeats-domain containing 2 (YEATS2) overexpression, which enhances tumor progression via the PI3K/AKT pathway. Our study delineates YEATS2’s oncogenic functions in HCC and its potential as a prognostic and predictive biomarker. Through comprehensive in vitro and bioinformatics analyses, we reveal that YEATS2 promotes cell proliferation, invasion, and epithelial-mesenchymal transition (EMT).
Product: Human YEATS domain-containing protein 2 (YEATS2) ELISA Kit
Pub Date:2025-07-29 IF: 3.800
Endophilin A2 (EPA2) is a member of the Endophilin family. The relationship between EPA2 and SLE pathogenesis is unclear.Plasma levels of EPA2 in SLE patients and healthy controls were detected by ELISA, and EPA2 mRNA levels of SLE patients were explored by qRT-PCR. EPA2 siRNA adenovirus was further injected into pristane-induced lupus mice, and the histological and serological changes were observed.
Product: Human Endophilin-A2 (SH3GL1) ELISA Kit
Pub Date:2025-07-01 IF: 2.000
Microvascular invasion (MVI) is a major determinant of poor prognosis in hepatocellular carcinoma (HCC). However, reliable noninvasive biomarkers for the preoperative evaluation and diagnosis of MVI are urgently needed in clinical practice.
Product: Human Phosphoacetylglucosamine mutase (PGM3) ELISA Kit
Pub Date:2025-06-10 IF: 8.300
Chronic pain is a global health issue that affects as many as 20% of the population. Inflammatory pain, an important form of chronic pain, negatively impacts patients’ quality of life. Indolepropionic acid (IPA), a metabolite derived from the gut microbiota, has anti-inflammatory properties.
Product: Mouse Interleukin 6 (IL-6) ELISA Kit
Pub Date:2025-05-22 IF: 2.500
The aim of the current study was to explore the association between urinary glycosaminoglycans and the onset of acute respiratory distress syndrome (ARDS) in sepsis patients. We conducted a prospective cohort study of 49 sepsis patients and collected clinical characteristics, urine, and blood samples within 24 h of admission to the Surgical Intensive Care Unit (SICU) of Peking University Third Hospital.
Product: Human Angiotensin 2 (ANG-2) ELISA Kit Human Krebs yon den Lundgen-6 (KL-6) ELISA Kit Human Receptor for advanced glycation end products (RAGE/AGER) ELISA Kit
Pub Date:2025-05-22 IF: 3.800